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UK funds human trials of potential COVID-19 vaccine from Imperial College London

first_imgTopics : Scientists at Imperial College London will start the first clinical trials of a potential COVID-19 vaccine this week with more than 45 million pounds ($56.50 million) in backing from the UK government and philanthropic donors.The trials are the first human tests of a new technology which the researchers say could transform vaccine development by enabling rapid responses to emerging diseases such as the COVID-19 infection caused by the new coronavirus.Robin Shattock, a professor at Imperial’s department of infectious disease who is leading this work, said that rather than using a part of the virus, as many vaccines do, this potential vaccine uses synthetic strands of the virus’ genetic material – RNA – which are packaged inside tiny fat droplets. When injected, it instructs muscle cells to produce virus proteins to protect against future infection. In animal tests, the vaccine was shown to be safe and showed “encouraging signs of an effective immune response”, Shattock’s team said in a statement.Around 300 healthy volunteers will receive two doses of the vaccine in the initial human trials to test whether it is safe in people and whether it produces an effective immune response against COVID-19. If it shows promise, larger trials with around 6,000 people would be planned for later this year.More than 100 potential COVID-19 vaccines are in development around the world, including several already in human trials from AstraZeneca, Pfizer, BioNtech, Johnson & Johnson, Merck, Moderna, Sanofi and CanSino Biologics.The Imperial trials come after the team won £41 million pounds in funding from the UK government plus £5 million in philanthropic donations.Business secretary Alok Sharma, said Imperial’s was “one of the world’s front-runners” and had Britain’s full backing. last_img read more

EC fires starting gun on development of ESG integration rules

first_imgThe request for technical advice was sent to the European Securities and Markets Authority (ESMA) and the EU supervisory authority for the insurance and occupational pension fund sector – EIOPA.In a letter to the heads of the two institutions, Olivier Guersent, the Commission’s director general for financial stability, financial services and capital markets union, said he invited EIOPA and ESMA to “closely liaise with and consult each other in the preparation of their technical advices to ensure consistency across sectors”. He suggested that Commission staff be invited to join as observers the ESMA and EIOPA working groups that will prepare the technical advice.According to the formal request itself they should provide advice on “how and where financial market participants are to integrate relevant sustainability risks within their business models and relevant procedures”. The Commission specifically referred to the areas of organisation requirements, operating conditions – in particular investment strategy and asset allocation, and risk management.The advice should take into account the size, nature, scale and complexity of financial market participants’ activities, it said. The request for advice comes after the Commission at the end of May announced a batch of legislative proposals to implement its sustainable finance action plan. One of the proposals is for a “regulation on disclosures relating to sustainable investments and sustainability risks”.At the time the Commission also said it was aimed at introducing “consistency and clarity” on how various financial market participants should integrate environmental, social and corporate governance (ESG) factors in their investment decision-making process.Exact requirements would be specified through delegated acts that it would adopt at a later stage, the Commission added. Its proposal sought to amend the IORP II directive to allow for delegated acts. However, the politician responsible for leading the European Parliament’s response to the Commission’s proposal deleted this provision in his amendments to the Commission proposal .The request for advice can be found here . The European Commission has asked two of the EU’s financial supervisory bodies for technical advice on potential amendments to EU rules to require the integration of sustainability risks in investment decision-making. The advice is being sought in relation to so-called delegated acts that would amend or introduce new rules under EU legislation addressing asset managers, insurers, insurance distributors and investment advisers.If accepted these rule changes would “explicitly require the integration of sustainability risks, i.e environmental, social and governance risks in the investment decision or advisory processes”.The Commission also said the supervisory authorities should be aware that a delegated act could be adopted under IORP II, the recently revised EU pension fund directive, “once and if the related empowerment […] is in place”.last_img read more

Glitzy Hawthorne digs hits market

first_imgThe master suite has a fireplace.There is another lounge room, a laundry and a guest bedroom with a bathroom on this floor.There is an outdoor kitchen next to the pool, as well as a steam room.Upstairs are five bedrooms, with the master suite taking up almost half of the floor. It even has its own balcony. Looking across the pool and into 93 Virginia Ave, Hawthorne.THIS Hawthorne house has it all.With a glitzy steam room by the pool, to a double sided fireplace and a master suite with its own retreat, dressing room and study, there is not anything more that could be added to the home at 93 Virginia Ave. The house at 93 Virginia Ave, Hawthorne, makes a bold statement.Kim Patterson and Stephen St Baker bought the property about a decade ago, and have since undertaken a number of renovations.“We built in the balcony off the main bedroom to add a large ladies dressing room,” Mr St Baker said.“We did total renovations of the bathroom and laundry in 2010, and retiled them in 2018, as well as laying a new blackbutt floor downstairs.” The living room is the seller’s favourite room.More from newsCrowd expected as mega estate goes under the hammer7 Aug 2020Hard work, resourcefulness and $17k bring old Ipswich home back to life20 Apr 2020The laying of the floorboards was one of Mr St Baker’s fondest memories of his time in the house.“Seeing the new blackbutt floor for the first time stands out as a memory, because it totally changed the feel of the house,” Mr St Baker said.center_img The glitzy steam room is fit for a mermaid.However, Mr St Baker said the living room downstairs was his favourite space.“I like the living room because it is the central room of the house and it looks out to the pool area,” he said.Video Player is loading.Play VideoPlayNext playlist itemMuteCurrent Time 0:00/Duration 0:51Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:51 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedQuality Levels720p720pHD576p576p432p432p270p270pAutoA, selectedAudio Tracken (Main), selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.This is a modal window. This modal can be closed by pressing the Escape key or activating the close button.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button.PlayMuteCurrent Time 0:00/Duration 0:00Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:00 Playback Rate1xFullscreenStarting your hunt for a dream home00:51 The kitchen is part galley style.The house has 364sq m of under roof living across two levels.On the lower level is a galley kitchen with a casual dining area, which flows to the living room.The living room is semi-separated from a formal dining area, and these rooms both open through bi-fold doors to the pool.last_img read more

Senators to question VFA termination before SC

first_imgSenate Minority leader Franklin Drilon. IAN PAUL CORDERO/PN Drilon said that the argument thesenators are eyeing to raise before the high court is similar to the one madeby opposition senators before the SC in questioning the Duterteadministration’s withdrawal from the Rome Statute, which created the InternationalCriminal Court (ICC). MANILA – Senate minority leader Franklin Drilon said senators are pushing with their bipartisan plan to file a petition before the Supreme Court challenging President Rodrigo Duterte’s move in terminating the Visiting Forces Agreement (VFA) between the Philippines and United States. President Rodrigo Duterte orderedForeign Affairs Secretary Teodoro “Teddyboy” Locsin Jr. in early February tosend notice to the US that it wants to end the VFA, despite his Cabinet membersadvising against it. Senate President Vicente “Tito” SottoIII and other senators, according to Drilon, will be crossing party lines toquestion the VFA’s termination without the Senate’s nod before the Supreme Court. “It is our firm belief that if treatiesand international agreements the President entered into cannot be valid withoutthe approval of the Senate, the termination of, or withdrawal from, the sameshould only be effective with the concurrence of the Senate,” the Ilonggolawmaker said in a statement.center_img He added that Sotto is already preparinga petition and has asked him to co-author it. The minority leader said heaccepted the Senate President’s invitation. Based on the 1987 Constitution, theSenate is required concur in treaties for these to be ratified but it does notsay if the Senate’s nod is also needed when the administration decides to exitfrom a treaty. “If the Supreme Court sides with their(Rome Statute) argument that the Senate’s concurrence is also required when theadministration decides to leave a treaty, then the Duterte administration’stermination of the VFA would also be considered invalid,” Drilon said. The US has received the Philippines’notice and US President Donald Trump has shrugged off the country’s terminationof the pact, which defense experts have warned will be detrimental to thePhilippines./PNlast_img read more

Cricket News Bangladesh PM Sheikh Hasina, West Bengal CM Mamata Banerjee To Ring Eden Bell To Start Pink Ball Test

first_img For all the Latest Sports News News, Cricket News News, Download News Nation Android and iOS Mobile Apps. New Delhi: The historic Pink Ball Test between India and Bangladesh at the Eden Gardens will have plenty of attention. Celebrities across all ends of the spectrum will be in attendance for the first Day-Night Test in India. In cricket, only two venues have the custom of ringing the bell and starting the Test match. One is Lord’s, considered to be the home of cricket and the other is Eden Gardens, Kolkata. Ahead of the Pink Ball Test, the Eden bell will be rung together by Bangladesh Prime Minister Sheikh Hasina and West Bengal Chief Minister Mamata Banerjee. Both will be seen at the bell ringing ceremony to start off the first day’s proceedings, Cricket Association of Bengal secretary Avishek Dalmiya told reporters here at Eden Gardens.  Bangladesh Premier Hasina will be among a starry gathering which will also include West Bengal governor Jagdeep Dhankar. The CAB will also felicitate a galaxy of Indian sports stars including cricket icon Sachin Tendulkar, Olympic champion Abhinav Bindra, tennis star Sania Mirza, world badminton champion PV Sindhu and six-time boxing world champion MC Mary Kom among others. Specially designed mementos will be given to the dignitaries while they will also make round of the stadium aboard golf carts, Avishek said. The CAB will also felicitate the team members of Bangladesh-India first ever Test in 2000, a game where Sourav Ganguly, the BCCI president, made his debut as Test captain.The Day-Night Test, played with a Pink Ball, came into realisation during the 2015 Test between Australia and New Zealand in Adelaide. The success of the Test, with regards to attendances at the stadium and the television ratings, charted a new course for Test matches.After being elected as the BCCI president, Sourav Ganguly had said that during his tenure, he will be pushing for the day and night Test. Ganguly said that the current Indian team under Virat Kohli was capable of doing well in the pink-ball Test format.Also Read | India Will Play First-Ever Day-Night Test Against Bangladesh At Eden Gardens”I must say that Virat Kohli is agreeable to it. There are reports that he does not want to play day-night Tests which is not the fact. So once the captain of India is agreeable to it, life becomes a lot easier. We will see how we can push it. The game needs to go forward. We all are thinking about this and we will do something about it. I am a firm believer in Day Night Tests. I don’t know when that will happen. But till the time I am around, I will be pushing for it,” Ganguly said.last_img read more

Badgers happy to be home

first_imgJEFF SCHORFHEIDE/Herald photoAfter playing on the road for all of its September matches, the Wisconsin volleyball team was getting used to playing away from the Field House.”It’s amazing to be back home,” senior Jackie Simpson said after Friday night’s victory over Purdue, Wisconsin’s first game back. “We missed it so much.”The Badgers had gotten so used to preparing for a game on the road that getting ready for their first Big Ten home game against the Boilermakers at the Field House felt strange to them.”It was really funny [Friday], because we were all [at the Field House] getting ready for the game, and we felt it was weird,” Simpson said. “Normally, we are getting ready for a game at a hotel. It was so nice to be home to just get ready to go and be out there with the fans. It was amazing.”After playing 10 straight matches on the road — and going 9-1 during that stretch — some Badgers were beginning to think they were never going to play another game in the Field House.”It was kind of unreal to be home tonight. This morning I didn’t even think we were going to have a home game,” senior Reineke said after Friday night’s match. “It is really nice to be back in front of our fans in the Field House and get their support again.”And that is exactly what the Badger fans did — they supported their team. With an average of just fewer than 6,000 fans a match this weekend cheering them on, the Badgers were able to pull off a pair of sweeps.With the Badgers facing a game point to Indiana during the second game of the match on Saturday night, everyone in attendance rose to their feet and cheered the Badgers to a come-from-behind victory.”This crowd is what really made me want to come here,” freshman Allison Wack said after the Badgers win over the Hoosiers. “It was the biggest factor for me. It’s great to play at home in tight games like that (and) having the momentum from the crowd helps a ton. Every play they get in the other team’s heads, which may have helped too. They are just a great asset to have here at the Field House.”And the Badgers were appreciative of all the fans that came to watch them play.”I want to say that was a great crowd,” head coach Pete Waite said after Saturday’s win. “7,074 were awesome. Thanks to everybody who came out tonight. That was awesome.”However, Wisconsin’s homecoming will be brief as the hit the road this weekend to take on rivals Minnesota and Iowa.Dolgner gets defensiveComing into this past weekend’s matches, Waite stressed the need for his team to improve defensively. It did a good job of doing so this weekend, out-digging both Purdue and Indiana, while not letting many balls hit the ground.One player who seemed to take Waite’s message to heart was sophomore outside hitter Brittany Dolgner. She led the team in digs in both matches with 11 against Purdue and nine against Indiana. “Being an outside hitter you are expected to hit a lot and get a lot of blocks and stuff,” Dolgner said. “Blocking and defense is the main thing that I’ve been working on this year.”For the year, Dolgner is second on the team in the category– behind senior libero Jocelyn Wack — averaging 2.24 digs per game.DuPont, Wack share timeSo far this year, sophomore Caity DuPont and freshman Allison Wack have been splitting time at the starting outside hitter opposite of Dolgner. This past weekend was no different.In the first match against Purdue, Waite started DuPont, and she came out swinging in Game 1. DuPont put down 3 while hitting at a .286 clip. In the second game, however, DuPont began to fade so Waite inserted Allison into the lineup.”We got [Allison Wack] in the end of the second game,” Waite said. “We had given [Purdue] a couple points, and we just wanted to finish things off. Looking at the stats after Game 2, I though Caity was fading a little bit. I think she hit .000 in that second game. She hit really well in the first game but just not as well the second. Al came in, and she’s got a different tempo and different shots, and she did a great job.”The next night against Indiana, Waite gave the starting nod to Wack instead.”I really just wanted to see how they both would respond to the starting spot,” Waite said. “We have to find out who’s best as a starter and who comes in off the bench well.”Wack responded well to getting the starting spot, finishing the game with 12 kills and only having three errors for a .391 hitting percentage. She also chipped in with two blocks.”All week in practice I’ve been working really hard on staying mentally tough. Last week, I had a pretty forgettable match at Northwestern,” said Wack, who two weekends ago hit -.143 against the Wildcats. “The biggest thing for me is just forgetting about it, wiping the slate clean and starting over. I just went out and worked my hardest and tried to shake off the errors.”last_img read more

OSU, IU top Wisconsin

first_imgThe Wisconsin women’s tennis team entered Sunday’s match at Nielsen Tennis Stadium against Ohio State still looking for its first win in Big Ten play. The Badgers — 7-5 against nonconference competition — had failed to record a victory in their first six conference matches of the season, and the 29th-ranked Buckeyes prolonged the Badgers’ recent woes, defeating them 5-2.Ohio State began the match by sweeping Wisconsin in the doubles portion of the competition, clinching a 1-0 lead in the match when Angela DiPastina and Christina Keesey claimed an 8-4 victory over junior Elizabeth Carpenter and freshman Jessica Seyferth of Wisconsin.In singles play, the Buckeyes won four of six matches to nail down the victory. Carpenter and freshman Emese Kardhordo picked up the Badgers’ two points of the match. Carpenter bounced back from a tough loss on Saturday, in which her opponent made a large comeback, to win a thrilling match over DiPastina, 6-3, 3-6, 6-4.“It’s always a scare when you go up early and the girl battles back, and that started happening again today,” Carpenter said. “I was up 3-0 and [DiPastina] battled back to 3-3, but I was able to weather her great playing and was able to win that next game and the match.”First-year coach Brian Fleishman was proud of his star player’s gutsy effort.“I think what helped [Carpenter] win today’s match was everything that’s happened up to this point,” Fleishman said. “She’s been playing No. 1 for us all year, except for one match, and she just used all that experience and kind of got fed up with losing and got herself over the hump today.”On Saturday, Wisconsin faced a formidable Indiana team looking to rebound from a tough home defeat at the hands of its in-state rival, No. 19 Notre Dame. The Hoosiers, ranked No. 28 in the nation, took care of business, sweeping the overmatched Badgers 7-0.In doubles play, Wisconsin’s No. 1 doubles team of Seyferth and Carpenter got the only win of the match with a victory over Indiana’s Brianna Williams and Katya Zamanova. The Badgers lost the other two doubles matches, and the Hoosiers took the early 1-0 lead.In the No. 1 singles match, Carpenter faced Alba Berdala, a talented junior from Spain. The match started promisingly for Carpenter, as she jumped out to a 4-0 advantage by capitalizing on the early mistakes of Berdala.Despite the strong start, however, Carpenter failed to win the first set. Berdala went on to win six consecutive games and handed Carpenter a demoralizing 6-4 first set defeat. The second set was competitive, but Carpenter, still visibly frustrated by her collapse in the first set, never fully recovered, and Berdala took the match in straight sets, 6-4, 6-4.The remainder of the singles competition went similarly for the Badgers, who lost all of their singles matches in straight sets aside from senior Morgan Tuttle, who won her first set in the No. 4 match before falling by a score of 2-6, 6-3, 6-3.“We competed well,” Fleishman said. “Still, we haven’t gotten the Big Ten win yet. That’s the one we’re looking for, but I think, for the most part, everybody competed to the best of their ability today, and that’s all we’re asking of them — to fight to the end and try to leave it out there on the court.”The Badgers are on the road next weekend, visiting Big Ten opponents Minnesota and Iowa on Apr. 12 and 13, respectively.last_img read more

Getting LeBron James to sit out ‘would take a lot of convincing’

first_img“That conversation hasn’t occurred, but I’m sure it can happen soon,” James said. “You kind of look at the rest of the games, and look at the percentages of what’s going on there in the future, and see what makes more sense for not only me but the team itself as well.”James, 34, has been limited to just 46 of 64 games this season due to a slight tear in his left groin. He is averaging 27.0 points, 8.0 assists and 8.7 rebounds per game. “That would take a lot of convincing from [coach] Luke [Walton] on up,” James told ESPN after the game. “Unless I’m hurt, I’m not sitting games.” While James confirmed that no one from the organization has approached him about pumping the brakes, he expects it could happen in the near future, and he’s not opposed to limiting his minutes if it’s beneficial for the team. He has increased his workload to a tiring 40-plus minutes in five of the Lakers’ past eight games, though L.A. has lost six of those contests. Related News NBA wrap: Lakers fall back in playoff race with loss to Clipperscenter_img The Lakers’ playoff hopes took another hit Monday, but LeBron James isn’t giving up.Even though his team inched closer to elimination from the postseason with a 113-105 loss to the Clippers, James insisted he won’t be shut down for the remainder of the season. Dwyane Wade breaks Michael Jordan’s record for most career blocks by a guardlast_img read more

NHL playoffs 2019: Knights call key penalty ‘a f—ing joke’ after Game 7 OT Sharks win

first_imgJonathan Marchessault branded the game-changing penalty handed to Cody Eakin as “embarrassing” after the Vegas Golden Knights were dumped out of the NHL playoffs by the San Jose Sharks in dramatic Game 7 that went to overtime.The Golden Knights, beaten in the Stanley Cup Finals by the Capitals last year, were leading 3-0 midway through the third period Tuesday of the deciding game at SAP Center and seemingly cruising into the second round. But the complexion of the contest changed when Eakin cross-checked Joe Pavelski, who collided with Paul Stastny before falling to the ice, where he appeared unconscious.A bleeding Pavelski was helped from the ice and Eakin was given a five-minute major penalty, during which time the Sharks rattled in four goals to take the lead. Marchessault did send the game into overtime with a late goal, but Barclay Goodrow won it for the hosts toward the end of the first extra period. Related News NHL playoffs 2019: Vegas’ Gerard Gallant upset with ‘clown’ Peter DeBoer’s comments It’s @bgoodrow23 with the goal to cap off The Insanity. #StanleyCup pic.twitter.com/79IFV1fVSq— NHL (@NHL) April 24, 2019″It’s a f—ing joke. They called five minutes for that?” Marchessault said of the crucial penalty. “Why don’t you have hockey replay or something? It changed the whole outcome of the game. Seriously. What is that?”It’s so disappointing. The game is not even close, it’s 3-0. Call the two [minutes], OK, but a five? With something you don’t even see? You just called the outcome. It’s a f—ing joke, that’s what it is. It’s embarrassing. …”It changes the whole outcome. Obviously human error exists, but it’s a fast game for everyone. I think everybody needed that extra help and I think they just got involved in the game.”They called a bad call and look where were we are now. Summer’s starting. Five months until Game 1 of the regular season starts.”Warning: NSFW language in video below.Jonathon Marchessault’s take on game 7…Embarrassing #vegasborn #vegasgoldenknights pic.twitter.com/pkAIOJHbsK— Knights Guild (@VGKKNIGHTS) April 24, 2019Golden Knights coach Gerard Gallant said the accidental nature of Pavelski’s fall did not warrant what proved to be such a costly penalty for his team.center_img “I’m sure you’ve all seen it on TV, there was no intent,” he said. “I feel awful that Joe got hurt; he’s a class player for their team, everybody loves him.”But there was no intent, there was no high stick that hit him in the face. When Stastny [came] out, they sort of got caught up and he fell and banged his head on the ice.”That’s the unfortunate part of it, it was an awful call. We’ve all seen it. It’s too bad we end up losing because of that because were we in control of the hockey game.” Canadiens’ Jesperi Kotkaniemi undergoes knee surgery, expected to be ready for training camplast_img read more

NHL trade news: Capitals send Matt Niskanen to Flyers for Radko Gudas

first_imgNiskanen was a critical building block toward Washington winning its first Stanley Cup title in 2017-18, though his production slipped this past season. He tallied 25 points in 80 games after posting 29 in just 68 regular-season games the year before. Thank you, Nisky. For everything. pic.twitter.com/jU8bfhb74N— Washington Capitals (@Capitals) June 14, 2019Niskanen told Philadelphia media on a conference call Friday that he was not shocked by “a little surprised” by the move. “I knew this is the time of year when these things can happen and I knew what kind of situation Washington was in, so I knew there was a possibility,” he said. Asked about his new team, he added: “I’ve played against these guys, the core of them, for quite a while now in a rivalry situation, whether it be with Pittsburgh or Washington. A couple playoff series. Their team has changed since I’ve been in the Metro division. Over the last few years they’ve gotten younger. The Capitals and Flyers are swapping veteran defensemen, with Matt Niskanen headed to Philadelphia and Radko Gudas coming to Washington. The deal, announced Friday, gives Philadelphia a Stanley Cup winner with ample playoff experience while providing blueline toughness — and salary cap relief — for the Capitals.  Gudas, 29, is entering the final year of a contract that will pay him $3.35 million next season, but the Flyers will cover 30 percent of that total. Niskanen, 32, has two seasons left on his deal at $5.75 million annually. That difference will give the Capitals more payroll flexibility this offseason as they determine whether to try and bring back the likes of Jakub Vrana and Andre Burakovsky or pursue outside free agents or trades.  Related News NHL free agency rumors: Sharks may be preparing to offer Erik Karlsson 8-year extension “I like the team. They have dangerous people, they’ve added young players with a lot of promise, hard to play against. I know they missed the playoffs last year, but I remember saying to a teammate, they should be doing better than they are. … They’re on the upswing I think. It was hard to play against the Flyers. Good organization, they play the game hard, they play to win. Lot of promise there. I’m excited about that.”Gudas will provide a different look on the Capitals’ blueline. He has ranked among the league leaders in penalty minutes throughout his career, though he racked up only 63 this season, and has been suspended multiple times by the NHL — most notably a 10-game ban in 2017 for slashing Mathieu Perreault.last_img read more